City MPG: 23. city. Highway MPG: 32. highway. 3.8 gals/ 100 miles. 2020 Mercedes-Benz E350 4matic 4 cyl, 2.0 L, Automatic 9-spd. Premium Gasoline. Not Available. Search by make for fuel efficient new and used cars and trucks 2009 Mercedes-Benz E-Class. 2009 Mercedes-Benz E320 Bluetec 6 cyl, 3.0 L, Automatic 7-spd 2023 Mercedes-Benz E-Class Fuel Economy & MPG. In terms of fuel economy, the E-Class is pretty average in the mid-size sedan segment. With no hardcore hybrid option, the best EPA estimates lie with the E 350 sedan which can get up to 23 mpg in the city and 31 on the highway. The 450 can match those figures and the E 53 sedan still gets 21 mpg The Edmunds TCO ® estimated monthly insurance payment for a 2014 Mercedes-Benz E-Class in Washington is: View detailed gas mileage data for the 2014 Mercedes-Benz E-Class. Use our handy tool to Fuel economy of the 2010 Mercedes-Benz E-Class. 1984 to present Buyer's Guide to Fuel Efficient Cars and Trucks. Estimates of gas mileage, greenhouse gas emissions, safety ratings, and air pollution ratings for new and used cars and trucks. All specifications, performance and fuel economy data of Mercedes-Benz E 200 (145 kW / 197 PS / 194 hp), edition of the year 2021 for Europe , including acceleration times 0-60 mph, 0-100 mph, 0-100 km/h, 0-200 km/h, quarter mile time, top speed, mileage and fuel economy, power-to-weight ratio, dimensions, drag coefficient, etc. The Mercedes-Benz E-Class brings a something-for-everyone philosophy to the midsize luxury market, offering sedans, coupes, cabriolets and station wagons from $56,000 to $122,150 and with 255 to Mercedes-Benz E-Class is a Sedan car available from Rs. 75.00 - 88.00 Lakh in India. E-Class is available in 4 colours and 3 versions. Fuel economy could be improved; however, it is still 1HBn.